STATISTICAL POWER AND PERFORMANCE OF STRATEGIES TO ANALYZE COMPOSITES OF SURVIVAL AND DURATION OF VENTILATION IN CLINICAL TRIALS

Statistical Power and Performance of Strategies to Analyze Composites of Survival and Duration of Ventilation in Clinical Trials

BACKGROUND:.Patients with acute hypoxemic respiratory failure are at high risk of death and prolonged time on the ventilator.Interventions often aim to reduce both mortality and time on the ventilator.Many methods have been proposed for analyzing these endpoints as a single composite outcome (days alive and free of ventilation), but it is unclear w

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ANALYSIS OF REGIONAL MIGRATION DISPARITIES IN ROMANIA

Migration is a complex phenomenon, highly studied globally.Thus, the analysis of the population mobility process is performed using an interdisciplinary approach, with strong links in sociology, history, economics, geography, demography and even psychology.All disciplines involved in the analysis of the phenomenon target different aspects of popula

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An insight on the impact of teleost whole genome duplication on the regulation of the molecular networks controlling skeletal muscle growth.

Fish muscle growth is a complex process regulated by multiple pathways, resulting on the net accumulation of proteins and the activation of myogenic progenitor cells.Around 350-320 million years ago, teleost fish went through a specific whole genome duplication (WGD) that expanded the existent gene repertoire.Duplicated genes can be retained by dif

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